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Study of the viral and microbial communities associated with Crohns disease: a metagenomic approach

NEJM 2021 Rubino D et al

The Precision Peptide Genetic Test reveals predispositions in key GLP-1 pathway genesGIPR rs1800437, GLP1R rs6923761, FTO rs9939609, and MC4R rs17782313that may correlate with efficacy and tolerance in clinical studies

Multiple molecules are upregulated or downregulated with lactate metabolism changing through diverse pathways

For many patients dealing with significant loose skin, surgical intervention is the most effective path forward